ID: ALA4400324
Type: Binding
Description: Potency index, ratio of IC50 of ceritinib to IC50 of compound for inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain expressed in baculovirus expression system L1196M mutant using srctide as substrate incubated for 1 hr by mobility shift assay
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4400324
Ratio IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
511.97 | 4.45 | 4.45 |