Basic Information
ID: ALA4400325
Type: Binding
Description: Potency index, ratio of IC50 of ceritinib to IC50 of compound for inhibition of recombinant human N-terminal GST-tagged ROS (1883 to 2347 residues) cytoplasmic domain expressed in baculovirus expression system using IRS1 as substrate incubated for 1 hr by mobility shift assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4400325
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 511.97 | 4.45 | 4.45 |