Assay Report Card

Basic Information

ID: ALA4400326

Type: Binding

Description: Potency index, ratio of IC50 of ceritinib to IC50 of compound for inhibition of recombinant human N-terminal GST-tagged ALK (1058 to 1620 residues) cytoplasmic domain G1202R mutant expressed in baculovirus expression system using srctide as substrate incubated for 1 hr by mobility shift assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
511.974.454.45