Basic Information
ID: ALA4400459
Type: ADME
Description: Inhibition of human recombinant N-terminal His-tagged and enterokinase cleavage site-fused KLK1 (19 to 262 residues) expressed in baculovirus infected Sf9 insect cells using R110 labelled GSK3162232A as substrate measured at 30 secs interval for 5 mins by FLINT assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4400459
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 409.68 | ||
| 254.53 | ||
| 317.59 | ||
| 477.68 | ||
| 427.67 | ||
| 331.61 | ||
| 318.57 | ||
| 318.57 | ||
| 423.71 | ||
| 462.12 | ||
| 427.67 | ||
| 477.68 | ||
| 302.57 | ||
| 477.68 | ||
| 302.57 | ||
| 288.54 | ||
| 443.14 | ||
| 318.57 | ||
| 443.14 | ||
| 423.71 | ||
| 427.67 | ||
| 439.71 | ||
| 477.68 | ||
| 302.57 | ||
| 318.57 | ||
| 318.57 | ||
| 304.54 | ||
| 409.68 |