Basic Information
ID: ALA4400612
Type: Binding
Description: Antagonist activity at P2X7R in Swiss Webster mouse peritoneal macrophages assessed as inhibition of ATP-induced propidium iodide uptake preincubated for 10 mins followed by ATP induction for 25 mins and subsequent propidium iodide addition for last 5 mins by fluorescence microscopic analysis
Organism: Mus musculus
Strain: Swiss Webster
Activity Charts
Bioactivity
Activity Types for Assay ALA4400612
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 474.57 | 3.82 | 3.82 |
| 854.04 | 9.31 | 9.31 |
| 341.37 | 2.16 | 2.16 |
| 317.73 | 2.08 | 2.08 |
| 297.31 | 2.25 | 2.25 |
| 317.30 | 2.57 | 2.57 |
| 313.31 | 1.52 | 1.52 |
| 283.29 | 1.86 | 1.86 |