Basic Information
ID: ALA4400621
Type: Binding
Description: Agonist activity at recombinant human TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium level after 30 mins by Fura-2 AM/Pluronic F-127 probe based fluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Transient receptor potential cation channel subfamily V member 4(ALA3119)
Document: ALA4400507
Agonist activity at recombinant human TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium level after 30 mins by Fura-2 AM/Pluronic F-127 probe based fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4400621
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 420.41 | 3.68 | 3.68 |
| 448.47 | 4.21 | 4.21 |
| 410.45 | 2.45 | 2.45 |
| 448.46 | 4.32 | 4.32 |
| 430.48 | 4.07 | 4.07 |
| 368.41 | 2.29 | 2.29 |
| 406.38 | 3.30 | 3.30 |
| 438.50 | 2.83 | 2.83 |
| 655.63 | 3.36 | 3.36 |
| 382.44 | 2.68 | 2.68 |
| 422.38 | 3.18 | 3.18 |
| 438.45 | 3.89 | 3.89 |
| 380.47 | 3.40 | 3.40 |
| 428.51 | 3.87 | 3.87 |
| 434.44 | 4.07 | 4.07 |
| 422.38 | 3.18 | 3.18 |
| 570.56 | 5.18 | 5.18 |
| 422.38 | 3.18 | 3.18 |
| 422.38 | 3.18 | 3.18 |