Basic Information
ID: ALA4400695
Type: Binding
Description: Activation of wild type recombinant human lysosomal beta-glucocerebrosidase at 0.048 to 100 uM using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: Beta-glucocerebrosidase(ALA2179)
Document: ALA4400509
Activation of wild type recombinant human lysosomal beta-glucocerebrosidase at 0.048 to 100 uM using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by fluorescence assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4400695
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 342.40 | 4.18 | 4.18 |
| 366.43 | 4.20 | 4.20 |
| 356.43 | 4.21 | 4.21 |
| 382.47 | 4.74 | 4.74 |
| 354.46 | 4.76 | 4.76 |
| 361.47 | 4.87 | 4.87 |
| 380.50 | 5.15 | 5.15 |
| 384.48 | 4.99 | 4.99 |
| 356.43 | 4.21 | 4.21 |
| 370.46 | 4.60 | 4.60 |
| 384.47 | 4.33 | 4.33 |
| 318.42 | 4.46 | 4.46 |
| 383.48 | 4.94 | 4.94 |
| 381.48 | 4.27 | 4.27 |
| 378.44 | 4.27 | 4.27 |
| 366.47 | 5.08 | 5.08 |
| 345.40 | 4.41 | 4.41 |
| 355.44 | 4.81 | 4.81 |
| 377.45 | 4.74 | 4.74 |
| 370.46 | 4.34 | 4.34 |
| 370.46 | 4.60 | 4.60 |
| 370.41 | 4.06 | 4.06 |
| 368.48 | 5.15 | 5.15 |
| 396.49 | 4.99 | 4.99 |
| 370.46 | 4.60 | 4.60 |
| 377.45 | 4.74 | 4.74 |
| 376.46 | 5.48 | 5.48 |
| 370.46 | 4.60 | 4.60 |
| 340.43 | 4.37 | 4.37 |
| 345.40 | 4.41 | 4.41 |
| 306.37 | 2.92 | 2.92 |
| 384.44 | 4.10 | 4.10 |
| 357.42 | 3.60 | 3.60 |
| 361.47 | 4.87 | 4.87 |
| 384.44 | 3.97 | 3.97 |
| 367.41 | 4.47 | 4.47 |
| 304.40 | 4.07 | 4.07 |
| 382.47 | 4.74 | 4.74 |
| 380.50 | 5.29 | 5.29 |
| 354.41 | 4.09 | 4.09 |
| 384.44 | 3.97 | 3.97 |
| 368.44 | 4.35 | 4.35 |