Induction of post-ER GCase activity in fibroblast cells harboring N370S/84GG double mutant derived from Gaucher's disease patient at 5 to 15 uM using ...

Basic Information

ID: ALA4400709

Type: Binding

Description: Induction of post-ER GCase activity in fibroblast cells harboring N370S/84GG double mutant derived from Gaucher's disease patient at 5 to 15 uM using PFB-FDGlu as substrate preincubated for 3 days followed by substrate addition and measured after 1 hr for every 20 mins in presence of bafilomycin by fluorescence assay

Format: BAO_0000219

Organism: Homo sapiens

Target:  Unchecked(ALA612545)

Document:  ALA4400509

Induction of post-ER GCase activity in fibroblast cells harboring N370S/84GG double mutant derived from Gaucher's disease patient at 5 to 15 uM using PFB-FDGlu as substrate preincubated for 3 days followed by substrate addition and measured after 1 hr for every 20 mins in presence of bafilomycin by fluorescence assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
384.443.973.97