Basic Information
ID: ALA4400740
Type: Binding
Description: Poison activity at recombinant human topoisomerase-1 assessed as stabilization of covalent topo-1-DNA cleavage complex by measuring nicked DNA formation using supercoiled pBR322 DNA as substrate after 60 mins by agarose gel electrophoresis method
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA topoisomerase I(ALA1781)
Document: ALA4400511
Poison activity at recombinant human topoisomerase-1 assessed as stabilization of covalent topo-1-DNA cleavage complex by measuring nicked DNA formation using supercoiled pBR322 DNA as substrate after 60 mins by agarose gel electrophoresis method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4400740
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.47 | 3.34 | 3.34 |
| 382.49 | 3.95 | 3.95 |