Basic Information
ID: ALA4401117
Type: Binding
Description: Inhibition of PTP1B in mouse C2C12 cells assessed as suppression of PA-induced insulin resistance by measuring increase in insulin-mediated IRS1 phosphorylation at Y632 residue preincubated for 1 hr followed by palmitic acid stimulation for 16 hrs and subsequent insulin addition measured after 30 mins by Western blot analysis
Organism: Mus musculus
Cell type: C2C12
Activity Charts
Bioactivity
Activity Types for Assay ALA4401117
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 547.20 | 7.14 | 7.14 |