Basic Information
ID: ALA4401323
Type: Binding
Description: Inhibition of HIV1 reverse transcriptase RNase H expressed in Escherichia coli JM109 using RNA/DNA duplex substrate HTS-1
Format: BAO_0000019
Organism: Human immunodeficiency virus 1
Target: Human immunodeficiency virus type 1 reverse transcriptase(ALA247)
Document: ALA4400534
Inhibition of HIV1 reverse transcriptase RNase H expressed in Escherichia coli JM109 using RNA/DNA duplex substrate HTS-1: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4401323
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 444.42 | 0.91 | 0.91 |
| 419.38 | 1.35 | 1.35 |
| 381.40 | 3.99 | 3.99 |
| 326.28 | 1.81 | 1.81 |
| 336.35 | 2.29 | 2.29 |
| 366.33 | 1.46 | 1.46 |
| 308.29 | 1.67 | 1.67 |
| 308.29 | 1.67 | 1.67 |
| 322.32 | 1.98 | 1.98 |
| 290.23 | -0.21 | -0.21 |
| 377.40 | 2.56 | 2.56 |
| 260.25 | 0.62 | 0.62 |
| 250.19 | 0.14 | 0.14 |
| 329.36 | 1.51 | 1.51 |
| 340.31 | 2.12 | 2.12 |
| 333.30 | 1.54 | 1.54 |
| 300.19 | 1.02 | 1.02 |
| 366.37 | 2.14 | 2.14 |
| 360.73 | 2.46 | 2.46 |
| 376.29 | 2.69 | 2.69 |
| 338.32 | 1.68 | 1.68 |
| 368.35 | 1.69 | 1.69 |
| 366.37 | 2.14 | 2.14 |
| 246.22 | 0.31 | 0.31 |