Basic Information
ID: ALA4401444
Type: Binding
Description: Inhibition of covalent binding of 50 uM (Z)-N-(2-(2-(4-(2,8-Diethyl-5,5-difluoro-1,3,7,9-tetramethyl-5H-4lambda4,5lambda4-dipyrrolo[1,2-c:2',1'-f ][1,3,2]diazaborinin-10-yl)phenoxy)-acetamido)ethyl)-2,4-dimethyl-5-((2-oxo-5-(vinylsulfon-amido)-indolin-3-ylidene)methyl)-1H-pyrrole-3-carboxamide to recombinant human FLT3 D835Y mutant (571 to 993 residues) expressed in baculovirus expression system at 100 uM by Western blot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4401444
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 398.48 | 3.33 | 3.33 |
| 378.38 | 1.03 | 1.03 |
| 471.99 | 3.37 | 3.37 |
| 485.61 | 3.08 | 3.08 |
| 397.46 | 3.45 | 3.45 |
| 397.46 | 3.45 | 3.45 |