Assay Report Card

Basic Information

ID: ALA4401513

Type: Binding

Description: Inhibition of N-terminal GST-tagged recombinant full length human DNMT1 (2 to 1632 residues) using poly(dI-dC)):poly(dI-dC) as substrate preincubated for 20 mins followed by [3H]-SAM and measured after 60 mins by scintillation counting

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
509.745.845.84
523.775.445.44