Assay Report Card

Basic Information

ID: ALA4401579

Type: Functional

Description: Induction of DNA damage in tumors of human NCI-H526 cells xenografted in nu/nu mouse assessed as increase in gammaH2AX intensity at 100 mg/kg, po administered QD for 9 days in liposomal formulation and measured on day 6 post dose by IHC-staining based microscopy

Organism: Homo sapiens

Cell type: NCI-H526

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
346.825.015.01