Antiangiogenic activity in tumors of human NCI-H526 cells xenografted in nu/nu mouse assessed as blood vessel formation by measuring CD31 intensity at...

Basic Information

ID: ALA4401583

Type: Functional

Description: Antiangiogenic activity in tumors of human NCI-H526 cells xenografted in nu/nu mouse assessed as blood vessel formation by measuring CD31 intensity at 100 mg/kg, po administered QD for 9 days in liposomal formulation and measured on day 9 post dose by IHC-staining based microscopy relative to control

Format: BAO_0000218

Organism: Homo sapiens

Cell type: NCI-H526

Target:  NCI-H526(ALA2366102)

Document:  ALA4400541

Antiangiogenic activity in tumors of human NCI-H526 cells xenografted in nu/nu mouse assessed as blood vessel formation by measuring CD31 intensity at 100 mg/kg, po administered QD for 9 days in liposomal formulation and measured on day 9 post dose by IHC-staining based microscopy relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
346.825.015.01