Basic Information
ID: ALA4401740
Type: Binding
Description: Inhibition of mouse GAT-1 assessed as percentage of remaining specific binding of NO711 at 1 uM after 4 hrs by LC-ESI-MS/ms analysis relative to control
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4401740
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 107.11 | 0.89 | 0.89 |
| 107.11 | 0.89 | 0.89 |
| 122.12 | 1.20 | 1.20 |
| 106.12 | 1.50 | 1.50 |
| 198.22 | 3.29 | 3.29 |
| 212.25 | 3.08 | 3.08 |
| 212.25 | 3.08 | 3.08 |
| 182.22 | 3.17 | 3.17 |
| 182.22 | 3.17 | 3.17 |
| 182.22 | 3.17 | 3.17 |
| 136.15 | 1.51 | 1.51 |
| 151.12 | 1.41 | 1.41 |
| 151.12 | 1.41 | 1.41 |
| 136.15 | 1.51 | 1.51 |
| 151.12 | 1.41 | 1.41 |
| 162.21 | 2.71 | 2.71 |
| 157.17 | 2.05 | 2.05 |
| 146.15 | 1.38 | 1.38 |
| 198.22 | 3.29 | 3.29 |
| 256.18 | 3.66 | 3.66 |
| 157.17 | 2.05 | 2.05 |
| 172.19 | 1.68 | 1.68 |
| 198.22 | 3.29 | 3.29 |
| 107.11 | 0.89 | 0.89 |
| 156.18 | 2.65 | 2.65 |
| 200.21 | 3.31 | 3.31 |
| 200.21 | 3.31 | 3.31 |
| 200.21 | 3.31 | 3.31 |
| 218.20 | 3.44 | 3.44 |
| 218.20 | 3.44 | 3.44 |
| 218.20 | 3.44 | 3.44 |
| 216.67 | 3.82 | 3.82 |
| 216.67 | 3.82 | 3.82 |
| 216.67 | 3.82 | 3.82 |
| 200.21 | 3.31 | 3.31 |
| 234.66 | 3.96 | 3.96 |
| 251.11 | 4.47 | 4.47 |
| 218.20 | 3.44 | 3.44 |
| 218.20 | 3.44 | 3.44 |
| 234.66 | 3.96 | 3.96 |
| 234.66 | 3.96 | 3.96 |
| 156.18 | 2.65 | 2.65 |
| 150.13 | 1.23 | 1.23 |
| 388.41 | 3.78 | 3.78 |
| 320.35 | 1.56 | 1.56 |
| 342.40 | 3.09 | 3.09 |
| 356.22 | 1.99 | 1.99 |
| 370.42 | 3.64 | 3.64 |
| 387.87 | 3.55 | 3.55 |
| 410.90 | 4.35 | 4.35 |
| 177.23 | 2.35 | 2.35 |
| 244.22 | 3.03 | 3.03 |
| 295.12 | 4.20 | 4.20 |
| 321.33 | 1.74 | 1.74 |
| 186.01 | 1.66 | 1.66 |
| 388.41 | 3.78 | 3.78 |
| 171.20 | 2.29 | 2.29 |
| 292.38 | 2.00 | 2.00 |
| 201.20 | 2.70 | 2.70 |
| 421.32 | 4.81 | 4.81 |
| 342.40 | 2.02 | 2.02 |
| 306.36 | 1.84 | 1.84 |
| 217.66 | 3.21 | 3.21 |
| 276.34 | 1.83 | 1.83 |
| 404.87 | 4.29 | 4.29 |
| 386.88 | 4.15 | 4.15 |
| 409.41 | 3.64 | 3.64 |
| 316.36 | 1.71 | 1.71 |
| 206.24 | 3.81 | 3.81 |
| 206.24 | 3.81 | 3.81 |
| 186.21 | 2.66 | 2.66 |
| 368.43 | 3.63 | 3.63 |
| 269.10 | 4.61 | 4.61 |
| 174.17 | 2.79 | 2.79 |
| 388.41 | 3.78 | 3.78 |
| 366.46 | 3.62 | 3.62 |
| 188.25 | 3.23 | 3.23 |
| 232.28 | 4.32 | 4.32 |
| 386.88 | 4.15 | 4.15 |
| 217.66 | 3.21 | 3.21 |
| 170.21 | 2.96 | 2.96 |
| 370.42 | 3.64 | 3.64 |
| 347.44 | 2.69 | 2.69 |
| 183.21 | 2.56 | 2.56 |
| 197.24 | 2.87 | 2.87 |
| 344.39 | 3.13 | 3.13 |
| 439.31 | 4.95 | 4.95 |
| 358.46 | 3.56 | 3.56 |
| 327.38 | 2.38 | 2.38 |
| 326.40 | 2.99 | 2.99 |
| 376.46 | 4.14 | 4.14 |
| 332.43 | 3.05 | 3.05 |
| 388.41 | 3.78 | 3.78 |
| 172.18 | 2.36 | 2.36 |
| 444.84 | 4.77 | 4.77 |
| 239.20 | 3.31 | 3.31 |
| 274.62 | 4.43 | 4.43 |
| 321.33 | 1.74 | 1.74 |
| 196.25 | 3.02 | 3.02 |
| 150.18 | 1.40 | 1.40 |
| 186.01 | 1.66 | 1.66 |
| 356.22 | 1.99 | 1.99 |
| 370.42 | 3.64 | 3.64 |
| 327.38 | 2.38 | 2.38 |
| 226.23 | 2.89 | 2.89 |
| 188.25 | 3.23 | 3.23 |
| 188.19 | 1.86 | 1.86 |
| 252.10 | 3.87 | 3.87 |
| 352.43 | 3.50 | 3.50 |
| 257.14 | 4.53 | 4.53 |
| 387.87 | 3.55 | 3.55 |
| 353.42 | 2.90 | 2.90 |
| 382.49 | 3.30 | 3.30 |
| 212.27 | 2.96 | 2.96 |
| 221.64 | 3.12 | 3.12 |
| 186.01 | 1.66 | 1.66 |
| 320.39 | 2.00 | 2.00 |
| 356.22 | 1.99 | 1.99 |
| 183.21 | 2.56 | 2.56 |
| 422.31 | 4.20 | 4.20 |
| 194.23 | 3.07 | 3.07 |
| 190.18 | 2.03 | 2.03 |
| 341.41 | 2.62 | 2.62 |
| 292.33 | 1.54 | 1.54 |
| 340.42 | 3.30 | 3.30 |
| 414.43 | 3.37 | 3.37 |
| 396.44 | 3.23 | 3.23 |
| 201.20 | 2.70 | 2.70 |
| 217.66 | 3.21 | 3.21 |
| 364.45 | 3.40 | 3.40 |
| 367.45 | 3.20 | 3.20 |
| 306.36 | 1.84 | 1.84 |
| 391.86 | 3.45 | 3.45 |
| 430.89 | 3.88 | 3.88 |
| 187.24 | 2.45 | 2.45 |
| 222.33 | 3.91 | 3.91 |
| 402.49 | 4.65 | 4.65 |
| 277.32 | 1.23 | 1.23 |
| 404.87 | 4.29 | 4.29 |
| 172.18 | 2.76 | 2.76 |
| 427.35 | 4.87 | 4.87 |
| 382.46 | 3.41 | 3.41 |
| 371.41 | 3.03 | 3.03 |
| 368.43 | 3.63 | 3.63 |
| 357.45 | 3.05 | 3.05 |
| 356.22 | 1.99 | 1.99 |
| 277.32 | 1.23 | 1.23 |
| 387.87 | 3.55 | 3.55 |
| 122.17 | 1.40 | 1.40 |
| 326.40 | 2.99 | 2.99 |
| 360.39 | 2.36 | 2.36 |
| 358.46 | 3.56 | 3.56 |
| 321.33 | 1.74 | 1.74 |
| 232.28 | 4.32 | 4.32 |
| 356.42 | 3.00 | 3.00 |
| 186.01 | 1.66 | 1.66 |
| 277.32 | 1.23 | 1.23 |
| 392.55 | 4.24 | 4.24 |
| 358.40 | 2.19 | 2.19 |
| 240.69 | 4.02 | 4.02 |
| 260.68 | 3.55 | 3.55 |
| 352.43 | 3.50 | 3.50 |
| 352.43 | 3.50 | 3.50 |
| 388.41 | 3.78 | 3.78 |
| 465.33 | 4.54 | 4.54 |
| 342.40 | 2.69 | 2.69 |
| 353.42 | 2.90 | 2.90 |
| 404.87 | 4.29 | 4.29 |
| 382.46 | 3.41 | 3.41 |
| 386.88 | 4.15 | 4.15 |
| 376.46 | 4.14 | 4.14 |
| 426.39 | 3.99 | 3.99 |
| 370.42 | 3.64 | 3.64 |
| 402.49 | 4.65 | 4.65 |
| 368.43 | 3.63 | 3.63 |
| 371.41 | 3.03 | 3.03 |