Basic Information
ID: ALA4401742
Type: Binding
Description: Inhibition of mouse GAT-1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition and measured after 4 mins by scintillation counting analysis
Format: BAO_0000219
Organism: Mus musculus
Cell type: HEK293
Target: GABA transporter 1(ALA5445)
Document: ALA4400545
Inhibition of mouse GAT-1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition and measured after 4 mins by scintillation counting analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4401742
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 455.77 | 4.73 | 4.73 |
| 441.33 | 4.29 | 4.29 |
| 457.79 | 4.81 | 4.81 |
| 424.88 | 3.78 | 3.78 |
| 422.86 | 3.70 | 3.70 |
| 475.78 | 4.95 | 4.95 |
| 424.88 | 3.78 | 3.78 |
| 463.81 | 4.87 | 4.87 |
| 457.79 | 4.81 | 4.81 |
| 441.33 | 4.29 | 4.29 |