Basic Information
ID: ALA4401829
Type: Binding
Description: Inhibition of dephosphorylated IRE1alpha (G547 to L977 residues) (unknown origin) -dependent cleavage of FAM-labeled stem-loop RNA containing the XBP1 cleavage site preincubated for 30 mins followed by RNA XBP1 substrate addition and measured after 15 mins by FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4401829
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.87 | 3.61 | 3.61 |
| 472.98 | 5.18 | 5.18 |
| 487.01 | 5.42 | 5.42 |
| 352.83 | 3.76 | 3.76 |
| 443.94 | 5.50 | 5.50 |
| 368.83 | 3.52 | 3.52 |
| 504.52 | 6.92 | 6.92 |
| 337.81 | 4.35 | 4.35 |
| 459.94 | 5.26 | 5.26 |
| 505.00 | 5.56 | 5.56 |
| 338.80 | 3.75 | 3.75 |
| 338.80 | 3.75 | 3.75 |
| 381.87 | 3.43 | 3.43 |
| 465.99 | 4.01 | 4.01 |
| 505.00 | 5.56 | 5.56 |
| 395.90 | 3.63 | 3.63 |
| 509.01 | 3.10 | 3.10 |
| 443.94 | 5.52 | 5.52 |
| 443.94 | 5.50 | 5.50 |
| 395.90 | 3.68 | 3.68 |
| 423.91 | 3.79 | 3.79 |
| 338.80 | 3.75 | 3.75 |
| 429.92 | 5.49 | 5.49 |
| 505.00 | 5.56 | 5.56 |