Basic Information
ID: ALA4401960
Type: Binding
Description: Inhibition of human recombinant MAO-B expressed in insect cells at 1 uM using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 15 mins by resorufin dye-based fluorescence assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: Monoamine oxidase B(ALA2039)
Document: ALA4400552
Inhibition of human recombinant MAO-B expressed in insect cells at 1 uM using p-tyramine as substrate preincubated for 30 mins followed by substrate addition measured for 15 mins by resorufin dye-based fluorescence assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4401960
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 147.13 | 0.82 | 0.82 |
| 281.36 | 3.54 | 3.54 |
| 297.35 | 3.37 | 3.37 |
| 295.38 | 4.27 | 4.27 |
| 282.34 | 2.88 | 2.88 |
| 288.73 | 3.10 | 3.10 |
| 339.39 | 3.90 | 3.90 |
| 301.77 | 4.15 | 4.15 |
| 354.45 | 4.49 | 4.49 |
| 309.37 | 3.89 | 3.89 |
| 302.76 | 3.14 | 3.14 |
| 254.29 | 2.45 | 2.45 |
| 323.18 | 3.75 | 3.75 |
| 271.29 | 2.94 | 2.94 |
| 336.22 | 4.80 | 4.80 |
| 322.15 | 3.71 | 3.71 |
| 330.36 | 3.51 | 3.51 |
| 288.73 | 3.10 | 3.10 |
| 332.79 | 3.46 | 3.46 |
| 271.25 | 2.54 | 2.54 |
| 297.33 | 4.15 | 4.15 |
| 281.36 | 3.80 | 3.80 |
| 312.37 | 3.20 | 3.20 |
| 282.34 | 2.88 | 2.88 |
| 287.70 | 3.05 | 3.05 |
| 328.37 | 2.82 | 2.82 |
| 267.33 | 3.63 | 3.63 |
| 302.76 | 3.14 | 3.14 |
| 268.32 | 2.49 | 2.49 |
| 342.40 | 3.38 | 3.38 |
| 340.42 | 3.93 | 3.93 |
| 336.31 | 3.95 | 3.95 |
| 293.37 | 4.32 | 4.32 |
| 296.37 | 3.36 | 3.36 |
| 336.31 | 3.95 | 3.95 |
| 293.37 | 4.05 | 4.05 |
| 257.26 | 2.90 | 2.90 |
| 308.16 | 4.07 | 4.07 |
| 254.29 | 2.45 | 2.45 |
| 288.73 | 3.10 | 3.10 |
| 299.35 | 4.10 | 4.10 |
| 285.32 | 3.63 | 3.63 |
| 272.28 | 2.58 | 2.58 |
| 316.33 | 2.95 | 2.95 |
| 268.32 | 2.49 | 2.49 |
| 285.27 | 2.58 | 2.58 |
| 297.33 | 4.15 | 4.15 |
| 318.76 | 2.98 | 2.98 |
| 346.81 | 4.02 | 4.02 |