Short-acting anaesthetic activity in Sprague-Dawley rat assessed as dose causing loss of righting reflex at 20 mg/kg/min followed by dose reduction to...

Basic Information

ID: ALA4401967

Type: Functional

Description: Short-acting anaesthetic activity in Sprague-Dawley rat assessed as dose causing loss of righting reflex at 20 mg/kg/min followed by dose reduction to 6.7 mg/kg/min dosed via infusion

Format: BAO_0000218

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Target:  Rattus norvegicus(ALA376)

Document:  ALA4400554

Short-acting anaesthetic activity in Sprague-Dawley rat assessed as dose causing loss of righting reflex at 20 mg/kg/min followed by dose reduction to 6.7 mg/kg/min dosed via infusion: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
237.732.902.90
337.853.613.61
381.903.633.63
322.842.752.75
350.893.533.53
365.904.254.25
351.874.004.00
337.853.613.61
383.873.463.46
365.904.254.25
365.904.394.39
343.882.702.70
336.863.183.18
339.822.462.46
323.823.223.22
308.812.402.40
336.863.183.18
322.842.792.79
294.782.142.14
390.964.454.45
295.772.442.44
371.864.264.26