Analgesic activity in Sprague-Dawley rat assessed as minimal dose for loss of pedal withdrawal reflex at 20 mg/kg/min followed by dose reduction to 6....

Basic Information

ID: ALA4401968

Type: Functional

Description: Analgesic activity in Sprague-Dawley rat assessed as minimal dose for loss of pedal withdrawal reflex at 20 mg/kg/min followed by dose reduction to 6.7 mg/kg/min dosed via infusion

Format: BAO_0000218

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Target:  Rattus norvegicus(ALA376)

Document:  ALA4400554

Analgesic activity in Sprague-Dawley rat assessed as minimal dose for loss of pedal withdrawal reflex at 20 mg/kg/min followed by dose reduction to 6.7 mg/kg/min dosed via infusion: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
237.732.902.90
337.853.613.61
381.903.633.63
322.842.752.75
350.893.533.53
365.904.254.25
351.874.004.00
337.853.613.61
383.873.463.46
365.904.254.25
365.904.394.39
343.882.702.70
336.863.183.18
339.822.462.46
323.823.223.22
308.812.402.40
336.863.183.18
322.842.792.79
294.782.142.14
390.964.454.45
295.772.442.44
371.864.264.26