Inhibition of full length recombinant human FASN using acetyl-CoA/malonyl-CoA as substrate preincubated for 60 mins followed by substrate addition and...

Basic Information

ID: ALA4402021

Type: Binding

Description: Inhibition of full length recombinant human FASN using acetyl-CoA/malonyl-CoA as substrate preincubated for 60 mins followed by substrate addition and measured after 90 mins in presence of NADPH

Format: BAO_0000357

Organism: Homo sapiens

Target: Fatty acid synthase(ALA4158)

Document: ALA4400560

Inhibition of full length recombinant human FASN using acetyl-CoA/malonyl-CoA as substrate preincubated for 60 mins followed by substrate addition and measured after 90 mins in presence of NADPH: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4402021

IC50

Total(28)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
402.85	2.96	2.96
364.45	2.82	2.82
403.48	2.65	2.65
425.87	2.96	2.96
350.42	2.16	2.16
364.45	2.55	2.55
409.42	2.44	2.44
378.47	2.94	2.94
391.43	2.30	2.30
401.47	2.71	2.71
402.85	2.96	2.96
414.89	2.82	2.82
402.85	2.96	2.96
362.47	3.83	3.83
407.50	2.77	2.77
403.48	2.65	2.65
352.43	2.41	2.41
364.45	2.82	2.82
401.47	2.71	2.71
389.46	2.64	2.64
391.43	2.30	2.30
401.47	2.71	2.71
409.42	2.44	2.44
407.50	2.77	2.77
404.47	2.05	2.05
425.87	2.96	2.96
364.45	2.82	2.82
402.45	2.11	2.11