Basic Information
ID: ALA4402156
Type: Binding
Description: Inhibition of JAK2 in Lewis rat T cells assessed as reduction in ConA/CD3/CD28-induced cell proliferation measured after 72 hrs by alamar blue staining based fluorescence assay
Format: BAO_0000219
Organism: Rattus norvegicus
Strain: Lewis
Target: Tyrosine-protein kinase JAK2(ALA1075225)
Document: ALA4400567
Inhibition of JAK2 in Lewis rat T cells assessed as reduction in ConA/CD3/CD28-induced cell proliferation measured after 72 hrs by alamar blue staining based fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4402156
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 380.41 | 0.97 | 0.97 |
| 410.48 | 1.39 | 1.39 |
| 437.51 | 1.00 | 1.00 |
| 365.24 | 1.60 | 1.60 |
| 396.46 | 1.00 | 1.00 |
| 366.39 | 0.58 | 0.58 |
| 352.40 | 1.08 | 1.08 |
| 351.21 | 1.52 | 1.52 |