Basic Information
ID: ALA4402160
Type: Binding
Description: Inhibition of JAK2 in human TF1 cells assessed as reduction in GM-CSF-induced STAT5 phosphorylation at 10 uM preincubated for 1 hr followed by GM-CSF stimulation and measured after 20 mins by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: Tyrosine-protein kinase JAK2(ALA2971)
Document: ALA4400567
Inhibition of JAK2 in human TF1 cells assessed as reduction in GM-CSF-induced STAT5 phosphorylation at 10 uM preincubated for 1 hr followed by GM-CSF stimulation and measured after 20 mins by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4402160
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 380.41 | 0.97 | 0.97 |
| 410.48 | 1.39 | 1.39 |
| 437.51 | 1.00 | 1.00 |
| 396.46 | 1.00 | 1.00 |
| 366.39 | 0.58 | 0.58 |
| 423.48 | 1.11 | 1.11 |