Basic Information
ID: ALA4402235
Type: Binding
Description: Inhibition of full-length human His6-tagged HPGDS expressed in Escherichia coli BL21 (DE3) using PGH2 as substrate measured after 90 to 120 secs by RapidFire high-throughput mass spectrometry assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4402235
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 341.41 | 2.28 | 2.28 |
| 284.36 | 3.31 | 3.31 |
| 354.45 | 3.30 | 3.30 |
| 299.33 | 1.25 | 1.25 |
| 285.30 | 0.86 | 0.86 |
| 321.28 | 1.45 | 1.45 |
| 344.37 | 3.89 | 3.89 |
| 285.35 | 1.73 | 1.73 |
| 300.36 | 2.28 | 2.28 |
| 286.33 | 1.89 | 1.89 |
| 230.27 | 1.99 | 1.99 |
| 294.31 | 1.96 | 1.96 |
| 216.24 | 1.60 | 1.60 |
| 368.46 | 3.10 | 3.10 |
| 285.33 | 2.95 | 2.95 |
| 381.40 | 3.44 | 3.44 |
| 403.39 | 1.76 | 1.76 |
| 299.33 | 1.20 | 1.20 |
| 301.30 | -0.17 | -0.17 |
| 285.30 | 0.86 | 0.86 |
| 299.33 | 1.25 | 1.25 |
| 372.47 | 3.07 | 3.07 |
| 216.24 | 1.60 | 1.60 |
| 273.29 | 0.85 | 0.85 |
| 308.34 | 3.10 | 3.10 |
| 296.33 | 1.91 | 1.91 |
| 282.30 | 1.90 | 1.90 |
| 339.27 | 1.75 | 1.75 |
| 378.42 | 3.90 | 3.90 |
| 244.29 | 2.38 | 2.38 |
| 282.30 | 2.53 | 2.53 |
| 421.38 | 2.06 | 2.06 |
| 342.44 | 3.30 | 3.30 |
| 367.41 | 1.17 | 1.17 |
| 309.32 | 1.86 | 1.86 |
| 272.30 | 1.50 | 1.50 |
| 333.35 | 2.67 | 2.67 |
| 259.26 | 0.46 | 0.46 |
| 154.17 | 2.11 | 2.11 |
| 258.32 | 2.77 | 2.77 |
| 272.30 | 1.50 | 1.50 |
| 396.41 | 4.19 | 4.19 |
| 273.29 | 0.85 | 0.85 |
| 318.38 | 3.66 | 3.66 |
| 202.21 | 1.34 | 1.34 |
| 230.27 | 1.95 | 1.95 |
| 296.33 | 1.91 | 1.91 |
| 285.30 | 0.86 | 0.86 |
| 308.34 | 2.52 | 2.52 |
| 292.34 | 3.17 | 3.17 |
| 286.33 | 1.89 | 1.89 |
| 296.33 | 1.91 | 1.91 |
| 268.28 | 2.22 | 2.22 |
| 284.28 | 0.69 | 0.69 |
| 282.30 | 2.23 | 2.23 |
| 272.30 | 1.76 | 1.76 |
| 294.31 | 1.96 | 1.96 |
| 282.30 | 2.23 | 2.23 |
| 314.35 | 1.00 | 1.00 |
| 268.28 | 2.22 | 2.22 |
| 294.31 | 1.96 | 1.96 |
| 286.33 | 2.15 | 2.15 |
| 327.38 | 1.98 | 1.98 |
| 270.33 | 2.92 | 2.92 |
| 282.30 | 2.23 | 2.23 |
| 285.30 | 0.86 | 0.86 |
| 184.20 | 2.12 | 2.12 |
| 308.34 | 2.52 | 2.52 |
| 268.28 | 2.22 | 2.22 |
| 314.39 | 2.67 | 2.67 |
| 184.20 | 2.12 | 2.12 |
| 283.29 | 1.29 | 1.29 |
| 287.28 | 0.40 | 0.40 |
| 363.44 | 1.40 | 1.40 |