Basic Information
ID: ALA4402363
Type: Binding
Description: Inhibition of recombinant human full length N-terminal GST-fused PKCi (1 to 587 residues) expressed in baculovirus expression system using 5-FAM-RFARKGSLRQKNV as substrate measured after 60 mins by caliper microfluidic mobility shift assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Protein kinase C iota(ALA2598)
Document: ALA4400577
Inhibition of recombinant human full length N-terminal GST-fused PKCi (1 to 587 residues) expressed in baculovirus expression system using 5-FAM-RFARKGSLRQKNV as substrate measured after 60 mins by caliper microfluidic mobility shift assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4402363
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 213.24 | 1.92 | 1.92 |
| 290.33 | 2.98 | 2.98 |
| 333.40 | 2.36 | 2.36 |
| 230.23 | 1.02 | 1.02 |
| 215.22 | 0.71 | 0.71 |
| 243.27 | 1.32 | 1.32 |
| 333.35 | 2.08 | 2.08 |
| 254.25 | 1.19 | 1.19 |
| 229.24 | 0.38 | 0.38 |
| 294.11 | 1.47 | 1.47 |
| 374.45 | 2.39 | 2.39 |
| 375.44 | 1.78 | 1.78 |
| 243.27 | 1.27 | 1.27 |
| 254.29 | 2.19 | 2.19 |
| 214.23 | 1.31 | 1.31 |
| 271.32 | 2.00 | 2.00 |
| 215.22 | 0.71 | 0.71 |
| 294.11 | 1.47 | 1.47 |
| 293.12 | 2.07 | 2.07 |
| 253.27 | 1.79 | 1.79 |