Basic Information
ID: ALA4402927
Type: Functional
Description: Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa;DTU 5 bloodstream trypomastigote infected in BALB/c mouse assessed as parasite-free adipose tissue in chronic phase at 20 mg/kg/day, po administered for 5 consecutive days starting from day 70 post infection followed by cyclophosphamide induced immunosuppression on day 80 post infection measured after day 100 post infection by PCR method relative to control
Format: BAO_0000218
Organism: Trypanosoma cruzi
Strain: MHOM/Pe/2011/Arequipa;DTU 5
Target: Trypanosoma cruzi(ALA368)
Document: ALA4402517
Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa;DTU 5 bloodstream trypomastigote infected in BALB/c mouse assessed as parasite-free adipose tissue in chronic phase at 20 mg/kg/day, po administered for 5 consecutive days starting from day 70 post infection followed by cyclophosphamide induced immunosuppression on day 80 post infection measured after day 100 post infection by PCR method relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4402927
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 260.25 | 1.11 | 1.11 |
| 344.84 | 3.44 | 3.44 |
| 378.39 | 3.81 | 3.81 |