Basic Information
ID: ALA4403076
Type: Functional
Description: Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa;DTU 5 epimastigote assessed as depolarization of mitochondrial membrane at IC50 measured after 72 hrs by rhodamine 123 and acridine orange staining based flow cytometry relative to control
Format: BAO_0000218
Organism: Trypanosoma cruzi
Strain: MHOM/Pe/2011/Arequipa;DTU 5
Target: Trypanosoma cruzi(ALA368)
Document: ALA4402517
Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa;DTU 5 epimastigote assessed as depolarization of mitochondrial membrane at IC50 measured after 72 hrs by rhodamine 123 and acridine orange staining based flow cytometry relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4403076
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 260.25 | 1.11 | 1.11 |
| 344.84 | 3.44 | 3.44 |
| 378.39 | 3.81 | 3.81 |