Basic Information
ID: ALA4403137
Type: Functional
Description: Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa;DTU 5 bloodstream trypomastigotes infected in BALB/c mouse assessed as reduction in serum Ig-G level in chronic phase at 20 mg/kg/day, po administered for 5 consecutive days starting from day 70 post infection followed by cyclophosphamide induced immunosuppression on day 80 post infection and measured at day 100 post infection by ELISA
Format: BAO_0000218
Organism: Trypanosoma cruzi
Strain: MHOM/Pe/2011/Arequipa;DTU 5
Target: Trypanosoma cruzi(ALA368)
Document: ALA4402517
Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa;DTU 5 bloodstream trypomastigotes infected in BALB/c mouse assessed as reduction in serum Ig-G level in chronic phase at 20 mg/kg/day, po administered for 5 consecutive days starting from day 70 post infection followed by cyclophosphamide induced immunosuppression on day 80 post infection and measured at day 100 post infection by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4403137
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 260.25 | 1.11 | 1.11 |
| 344.84 | 3.44 | 3.44 |
| 378.39 | 3.81 | 3.81 |