Basic Information
ID: ALA4403232
Type: Binding
Description: Inhibition of human C-terminal His10-tagged LOXL2 (Met1 to Gln774 residues) expressed in mouse NS0 cells using cadaverine hydrochloride as substrate preincubated for 1 hr followed by substrate addition by ROS-Glo assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Lysyl oxidase homolog 2(ALA3714029)
Document: ALA4402523
Inhibition of human C-terminal His10-tagged LOXL2 (Met1 to Gln774 residues) expressed in mouse NS0 cells using cadaverine hydrochloride as substrate preincubated for 1 hr followed by substrate addition by ROS-Glo assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4403232
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 70.09 | -0.14 | -0.14 |
| 376.53 | 3.82 | 3.82 |
| 392.53 | 2.84 | 2.84 |
| 407.54 | 3.11 | 3.11 |
| 402.42 | 2.85 | 2.85 |
| 303.41 | 3.19 | 3.19 |
| 362.48 | 2.40 | 2.40 |
| 330.43 | 3.10 | 3.10 |
| 359.48 | 3.14 | 3.14 |
| 260.38 | 1.71 | 1.71 |
| 304.40 | 2.59 | 2.59 |
| 304.40 | 2.59 | 2.59 |
| 422.55 | 2.81 | 2.81 |
| 412.52 | 1.24 | 1.24 |
| 422.55 | 2.77 | 2.77 |
| 352.42 | 1.97 | 1.97 |
| 360.46 | 3.11 | 3.11 |
| 441.98 | 3.76 | 3.76 |
| 362.48 | 2.40 | 2.40 |
| 220.32 | 0.79 | 0.79 |
| 332.43 | 0.84 | 0.84 |
| 476.52 | 3.52 | 3.52 |
| 372.51 | 4.23 | 4.23 |
| 386.54 | 4.40 | 4.40 |
| 422.55 | 2.81 | 2.81 |
| 421.57 | 3.42 | 3.42 |
| 268.36 | 1.67 | 1.67 |
| 426.52 | 2.64 | 2.64 |
| 408.53 | 2.51 | 2.51 |
| 344.46 | 3.34 | 3.34 |
| 425.53 | 3.25 | 3.25 |
| 266.37 | 3.94 | 3.94 |
| 358.49 | 3.66 | 3.66 |
| 368.87 | 2.49 | 2.49 |
| 304.40 | 2.59 | 2.59 |
| 408.53 | 2.51 | 2.51 |
| 412.52 | 1.24 | 1.24 |
| 254.34 | 1.43 | 1.43 |