Basic Information
ID: ALA4403458
Type: Binding
Description: Inhibition of Sprague-Dawley rat spleen microsome HO-1 preincubated for 10 mins followed by beta-NADPH addition and measured after 15 mins by gas chromatography
Format: BAO_0000251
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Spleen
Subcellular Fraction: Microsome
Target: Heme oxygenase 1(ALA5035)
Document: ALA4402532
Inhibition of Sprague-Dawley rat spleen microsome HO-1 preincubated for 10 mins followed by beta-NADPH addition and measured after 15 mins by gas chromatography: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4403458
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 429.97 | 4.66 | 4.66 |
| 262.31 | 3.43 | 3.43 |
| 268.36 | 3.81 | 3.81 |
| 290.37 | 3.55 | 3.55 |
| 236.27 | 2.92 | 2.92 |
| 430.96 | 4.78 | 4.78 |
| 214.27 | 2.08 | 2.08 |
| 216.28 | 2.74 | 2.74 |
| 263.30 | 2.83 | 2.83 |
| 240.31 | 2.64 | 2.64 |
| 280.12 | 1.85 | 1.85 |
| 383.33 | 5.97 | 5.97 |
| 277.33 | 2.75 | 2.75 |
| 350.89 | 5.72 | 5.72 |
| 232.35 | 3.46 | 3.46 |
| 338.88 | 5.86 | 5.86 |
| 316.45 | 5.06 | 5.06 |
| 246.31 | 1.89 | 1.89 |
| 255.10 | 3.07 | 3.07 |
| 322.46 | 4.13 | 4.13 |
| 460.98 | 4.06 | 4.06 |
| 276.34 | 3.36 | 3.36 |
| 200.28 | 2.91 | 2.91 |
| 228.34 | 3.69 | 3.69 |
| 218.32 | 2.82 | 2.82 |
| 324.85 | 5.47 | 5.47 |
| 260.38 | 2.85 | 2.85 |
| 369.31 | 5.58 | 5.58 |
| 358.84 | 4.89 | 4.89 |
| 395.34 | 5.83 | 5.83 |
| 341.21 | 4.20 | 4.20 |
| 304.44 | 5.13 | 5.13 |
| 241.29 | 2.04 | 2.04 |
| 289.55 | 3.73 | 3.73 |
| 292.38 | 3.40 | 3.40 |