Basic Information
ID: ALA4403678
Type: Binding
Description: Inhibition of COX2 in mouse RAW264.7 cells assessed as reduction in LPS-induced inflammation by measuring PGE2 level at 1 uM treated 1 hr after LPS stimulation and measured after 18 hrs by ELISA (Rvb = (2437 +/- 93.17 pg/mL)
Organism: Mus musculus
Cell type: RAW264.7
Activity Charts
Bioactivity
Activity Types for Assay ALA4403678
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 222.25 | -0.86 | -0.86 |
| 206.28 | 3.07 | 3.07 |
| 254.29 | 3.11 | 3.11 |
| 296.15 | 4.36 | 4.36 |
| 483.35 | 5.58 | 5.58 |
| 393.48 | 4.29 | 4.29 |
| 483.35 | 5.58 | 5.58 |
| 393.48 | 4.29 | 4.29 |
| 442.47 | 4.75 | 4.75 |
| 394.47 | 4.72 | 4.72 |
| 394.47 | 4.72 | 4.72 |
| 442.47 | 4.75 | 4.75 |