Assay Report Card

Basic Information

ID: ALA4403989

Type: ADME

Description: Inhibition of PI3Kgamma in mouse RAW264 cells assessed as reduction in C5a anaphylatoxin trifluoroacetate salt-induced AKT phosphorylation at T208 residue preincubated for 1 hr followed by C5a anaphylatoxin trifluoroacetate salt addition and measured after 3 mins by QuantaBlu substrate based fluorescence assay

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
380.411.581.58