Basic Information
ID: ALA4404018
Type: Binding
Description: Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated for 30 mins by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4404018
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 426.52 | 2.38 | 2.38 |
| 391.52 | 4.72 | 4.72 |
| 349.43 | 3.50 | 3.50 |
| 422.53 | 2.97 | 2.97 |
| 269.28 | 2.58 | 2.58 |
| 215.25 | 2.06 | 2.06 |
| 394.48 | 1.94 | 1.94 |
| 337.42 | 3.14 | 3.14 |
| 496.61 | 4.94 | 4.94 |
| 365.48 | 4.09 | 4.09 |
| 377.49 | 4.28 | 4.28 |
| 392.50 | 3.38 | 3.38 |
| 351.45 | 3.70 | 3.70 |
| 380.45 | 1.93 | 1.93 |
| 393.49 | 3.26 | 3.26 |
| 311.39 | 2.92 | 2.92 |
| 337.42 | 3.14 | 3.14 |
| 351.45 | 3.53 | 3.53 |
| 380.45 | 1.63 | 1.63 |
| 366.42 | 1.62 | 1.62 |
| 351.45 | 3.26 | 3.26 |
| 363.46 | 4.21 | 4.21 |
| 363.46 | 3.89 | 3.89 |
| 341.41 | 2.54 | 2.54 |
| 349.43 | 3.14 | 3.14 |
| 391.52 | 4.72 | 4.72 |
| 434.54 | 3.64 | 3.64 |