Basic Information
ID: ALA4404101
Type: Binding
Description: Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Bile acid receptor FXR(ALA2047)
Document: ALA4402557
Agonist activity at FXR transfected in human HEK293T cells o-expressing pGL3/hBSEP/luc incubated for 24 hrs by Steady-Glo reagent based luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4404101
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 420.63 | 5.11 | 5.11 |
| 487.94 | 5.17 | 5.17 |
| 603.59 | 7.28 | 7.28 |
| 484.35 | 2.92 | 2.92 |
| 404.47 | 2.76 | 2.76 |
| 536.51 | 4.85 | 4.85 |
| 501.36 | 3.66 | 3.66 |
| 530.37 | 3.36 | 3.36 |
| 390.49 | 3.12 | 3.12 |
| 452.94 | 3.97 | 3.97 |
| 483.37 | 3.52 | 3.52 |
| 511.42 | 4.56 | 4.56 |
| 511.42 | 4.26 | 4.26 |
| 501.36 | 3.66 | 3.66 |
| 430.51 | 3.40 | 3.40 |
| 362.43 | 2.58 | 2.58 |
| 469.34 | 3.51 | 3.51 |
| 460.58 | 4.27 | 4.27 |
| 444.96 | 3.79 | 3.79 |
| 438.92 | 3.41 | 3.41 |
| 501.36 | 3.66 | 3.66 |
| 444.54 | 3.64 | 3.64 |
| 550.49 | 4.38 | 4.38 |
| 483.37 | 3.52 | 3.52 |