Basic Information
ID: ALA4404277
Type: ADME
Description: Inhibition of recombinant human carbonic anhydrase 1 incubated for 6 hrs prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Carbonic anhydrase I(ALA261)
Document: ALA4402561
Inhibition of recombinant human carbonic anhydrase 1 incubated for 6 hrs prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4404277
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 222.25 | -0.86 | -0.86 |
| 324.45 | 0.61 | 0.61 |
| 383.52 | 0.09 | 0.09 |
| 390.42 | 1.34 | 1.34 |
| 344.39 | 1.95 | 1.95 |
| 405.39 | 1.24 | 1.24 |
| 374.42 | 1.95 | 1.95 |
| 396.83 | 2.74 | 2.74 |
| 350.42 | 2.01 | 2.01 |
| 378.84 | 2.60 | 2.60 |
| 382.83 | 1.95 | 1.95 |
| 352.80 | 1.94 | 1.94 |
| 439.29 | 2.09 | 2.09 |
| 394.84 | 1.98 | 1.98 |
| 370.79 | 2.08 | 2.08 |
| 431.70 | 2.70 | 2.70 |
| 360.40 | 1.33 | 1.33 |
| 389.39 | 1.85 | 1.85 |
| 378.84 | 2.60 | 2.60 |
| 256.28 | 0.25 | 0.25 |
| 385.41 | 1.20 | 1.20 |
| 387.25 | 2.59 | 2.59 |
| 378.39 | 1.47 | 1.47 |
| 420.45 | 1.35 | 1.35 |