Assay Report Card

Basic Information

ID: ALA4404284

Type: Binding

Description: Inhibition of N-terminal His6-sumo-tagged full length Staphylococcus aureus ClpP expressed in Escherichia coli BL2 (DE3) at 10 uM pre-incubated for 10 mins before Suc-LY-AMC addition and measured after 1 hr by fluorescence based assay relative to control

Organism: Staphylococcus aureus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
406.916.616.61
206.283.073.07
123.110.780.78
124.100.170.17
156.572.042.04
152.151.391.39
1297.30
150.181.701.70
136.151.691.69
123.110.780.78
175.191.791.79
321.381.811.81
178.232.682.68
140.111.521.52
167.121.291.29
384.25
164.202.512.51
191.012.692.69
156.572.042.04
212.121.201.20
164.161.591.59
182.171.401.40
350.466.206.20
518.47
173.171.931.93
167.001.251.25
129.12-0.65-0.65
157.561.431.43
517.13
182.181.401.40
628.767.247.24
127.100.680.68
166.181.701.70
182.131.441.44
285.300.990.99
185.111.431.43
271.280.900.90
143.171.151.15
152.980.860.86
424.315.185.18
157.561.431.43
940.681.691.69