Basic Information
ID: ALA4404682
Type: Binding
Description: Inhibition of GSTO1-1 in mouse bone marrow derived macrophage cells assessed as reduction in LPS-induced IL-1beta release by measuring IL1 beta level at 5 uM pretreated with LPS for 3 hrs followed by compound addition and measured after 1 hr by ELISA relative to control
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4404682
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 311.19 | 1.77 | 1.77 |
| 341.22 | 1.44 | 1.44 |
| 353.23 | 1.54 | 1.54 |
| 369.27 | 2.17 | 2.17 |
| 325.22 | 2.20 | 2.20 |
| 344.74 | 2.13 | 2.13 |
| 355.24 | 1.78 | 1.78 |
| 288.76 | 1.71 | 1.71 |
| 315.78 | 1.39 | 1.39 |
| 261.73 | 1.66 | 1.66 |
| 386.78 | 1.90 | 1.90 |