Basic Information
ID: ALA4404704
Type: Binding
Description: Inhibition of human PDE4D2 (86 to 413 residues) expressed in Escherichia coli BL21 codon-plus cells using [3H]cAMP as substrate incubated for 15 mins by liquid scintillation counting method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4404704
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 275.35 | 2.62 | 2.62 |
| 410.47 | 5.09 | 5.09 |
| 408.45 | 5.06 | 5.06 |
| 466.49 | 4.82 | 4.82 |
| 564.68 | 7.55 | 7.55 |
| 529.43 | 6.52 | 6.52 |
| 557.48 | 7.30 | 7.30 |
| 536.62 | 6.47 | 6.47 |
| 550.65 | 7.16 | 7.16 |
| 578.70 | 7.64 | 7.64 |
| 550.65 | 6.86 | 6.86 |
| 592.73 | 8.03 | 8.03 |
| 564.68 | 7.25 | 7.25 |
| 536.62 | 6.77 | 6.77 |
| 522.59 | 6.38 | 6.38 |
| 522.59 | 6.08 | 6.08 |
| 585.54 | 8.08 | 8.08 |
| 519.64 | 6.22 | 6.22 |
| 561.72 | 7.39 | 7.39 |
| 533.67 | 6.61 | 6.61 |
| 494.54 | 5.60 | 5.60 |
| 494.54 | 5.30 | 5.30 |
| 575.75 | 7.78 | 7.78 |
| 571.51 | 7.69 | 7.69 |
| 543.45 | 6.91 | 6.91 |
| 547.69 | 7.00 | 7.00 |
| 508.57 | 5.99 | 5.99 |