Basic Information
ID: ALA4404789
Type: Binding
Description: Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 15 uM acetyl coenzyme A and N-terminal histone H4 peptide (sequence SGRGKGGKGLGKGGAKRHRKV-GGK-biotin) as substrate incubated for 60 mins by Alpha screen technology
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4404789
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 344.37 | 2.60 | 2.60 |
| 322.36 | 2.01 | 2.01 |
| 418.42 | 3.26 | 3.26 |
| 338.36 | 1.85 | 1.85 |
| 378.43 | 2.77 | 2.77 |
| 420.20 | 2.05 | 2.05 |
| 373.20 | 2.21 | 2.21 |
| 352.39 | 2.24 | 2.24 |
| 370.40 | 3.12 | 3.12 |
| 366.41 | 2.63 | 2.63 |
| 336.39 | 2.40 | 2.40 |
| 294.31 | 1.45 | 1.45 |
| 404.39 | 2.96 | 2.96 |
| 404.39 | 2.96 | 2.96 |
| 336.39 | 2.57 | 2.57 |
| 378.30 | 2.35 | 2.35 |
| 366.41 | 2.48 | 2.48 |
| 352.39 | 2.24 | 2.24 |
| 308.33 | 1.76 | 1.76 |