Basic Information
ID: ALA4404830
Type: Binding
Description: Inhibition of JAK1/Tyk2 in human PBMC assessed as reduction in IFNalpha-induced STAT4 phosphorylation pre-incubated for 30 mins before IFNalpha stimulation for 30 mins AlphaLISAassay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4404830
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 390.49 | 3.97 | 3.97 |
| 418.42 | 3.78 | 3.78 |
| 487.61 | 3.79 | 3.79 |
| 489.62 | 3.42 | 3.42 |
| 293.37 | 3.87 | 3.87 |
| 408.51 | 2.99 | 2.99 |
| 475.64 | 4.34 | 4.34 |
| 417.52 | 3.77 | 3.77 |
| 389.46 | 3.13 | 3.13 |
| 434.54 | 3.52 | 3.52 |
| 444.51 | 4.56 | 4.56 |