Basic Information
ID: ALA4404837
Type: Binding
Description: Inhibition of JAK1/Tyk2 in human PBMC assessed as reduction in IL12 -induced STAT4 phosphorylation pre-incubated for 30 mins before IL12 stimulation for 30 mins AlphaLISAassay
Format: BAO_0000223
Organism: Homo sapiens
Target: JAK1/TYK2(ALA3301391)
Document: ALA4402578
Inhibition of JAK1/Tyk2 in human PBMC assessed as reduction in IL12 -induced STAT4 phosphorylation pre-incubated for 30 mins before IL12 stimulation for 30 mins AlphaLISAassay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4404837
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 408.51 | 2.99 | 2.99 |