ID: ALA4404864
Type: Functional
Description: Positive allosteric modulation at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-induced cAMP production measured after 1 hr in presence of 1 uM propionate by fluorescence plate reader assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Free fatty acid receptor 3(ALA5201)
Document: ALA4402580
Positive allosteric modulation at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-induced cAMP production measured after 1 hr in presence of 1 uM propionate by fluorescence plate reader assay: 1
Bioactivity
Activity Types for Assay ALA4404864
EC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
323.44 | 4.42 | 4.42 |
398.51 | 5.15 | 5.15 |
352.48 | 4.48 | 4.48 |
362.43 | 4.19 | 4.19 |
338.45 | 4.23 | 4.23 |
352.48 | 4.48 | 4.48 |
277.36 | 2.71 | 2.71 |
324.42 | 3.84 | 3.84 |
356.47 | 3.92 | 3.92 |
366.51 | 5.01 | 5.01 |
323.44 | 4.27 | 4.27 |
400.52 | 5.07 | 5.07 |
378.50 | 4.66 | 4.66 |
352.48 | 4.62 | 4.62 |
402.54 | 5.63 | 5.63 |
360.41 | 4.73 | 4.73 |