Assay Report Card

Basic Information

ID: ALA4405023

Type: Functional

Description: In vivo antibacterial activity against Staphylococcus aureus ATCC 29213 infected in C57BL/6 mouse assessed as reduction in bacterial burden by measuring log10 CFU/cornea at 0.3% administered topically as two times on day 1, four times on day 2 and two times on day 3 measured at 48 hrs post-final dose by 10 fold serial dilution method (Rvb = 6.5 +/- 0.7 log10CFU)

Organism: Staphylococcus aureus

Strain: ATCC 29213

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
375.401.981.98
401.442.372.37
2846.51