Basic Information
ID: ALA4405037
Type: Binding
Description: Inhibition of Trypanosoma brucei PDEB1 (565 to 918 residues) expressed in Escherichia coli BL21 (DE3) using cAMP as substrate by PDELight HTS cAMP phosphodiesterase Kit based
Organism: Trypanosoma brucei
Activity Charts
Bioactivity
Activity Types for Assay ALA4405037
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 508.59 | 3.12 | 3.12 |
| 464.55 | 3.36 | 3.36 |
| 534.63 | 3.65 | 3.65 |
| 566.65 | 4.18 | 4.18 |
| 550.66 | 3.00 | 3.00 |
| 552.67 | 3.22 | 3.22 |
| 462.55 | 2.87 | 2.87 |
| 475.57 | 3.90 | 3.90 |
| 502.58 | 2.75 | 2.75 |
| 590.72 | 3.92 | 3.92 |
| 592.74 | 4.15 | 4.15 |
| 568.67 | 4.41 | 4.41 |
| 475.57 | 3.73 | 3.73 |
| 504.58 | 3.00 | 3.00 |
| 518.64 | 4.09 | 4.09 |
| 522.60 | 2.22 | 2.22 |
| 490.59 | 3.31 | 3.31 |
| 548.64 | 2.75 | 2.75 |
| 523.06 | 4.73 | 4.73 |
| 272.26 | 1.10 | 1.10 |
| 476.58 | 4.21 | 4.21 |
| 562.67 | 3.14 | 3.14 |
| 520.66 | 4.31 | 4.31 |
| 503.63 | 4.51 | 4.51 |
| 526.58 | 3.26 | 3.26 |
| 518.64 | 4.09 | 4.09 |
| 497.60 | 4.44 | 4.44 |
| 479.56 | 4.77 | 4.77 |
| 598.70 | 3.44 | 3.44 |
| 624.63 | 4.41 | 4.41 |
| 355.40 | 1.50 | 1.50 |
| 494.57 | 4.35 | 4.35 |
| 462.55 | 2.87 | 2.87 |
| 512.61 | 4.03 | 4.03 |
| 622.62 | 4.18 | 4.18 |
| 548.66 | 4.04 | 4.04 |
| 662.68 | 5.11 | 5.11 |
| 525.58 | 4.80 | 4.80 |
| 528.60 | 3.48 | 3.48 |
| 465.58 | 3.95 | 3.95 |
| 508.58 | 1.97 | 1.97 |
| 512.61 | 4.03 | 4.03 |
| 575.59 | 5.69 | 5.69 |
| 497.60 | 4.44 | 4.44 |
| 522.60 | 2.22 | 2.22 |
| 503.63 | 4.51 | 4.51 |