Basic Information
ID: ALA4405131
Type: Binding
Description: Inhibition of recombinant human C-terminal His-fusion tagged HDAC5 (657 to 1123 residues) expressed in baculovirus infected insect cells using fluorogenic HDAC class2a as substrate measured after 1 to 2 hrs by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4405131
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 302.37 | 2.58 | 2.58 |
| 348.36 | 2.98 | 2.98 |
| 514.53 | 5.36 | 5.36 |
| 421.47 | 2.56 | 2.56 |
| 562.59 | 3.74 | 3.74 |
| 562.59 | 3.74 | 3.74 |
| 512.57 | 3.83 | 3.83 |
| 526.60 | 4.22 | 4.22 |
| 561.61 | 4.35 | 4.35 |
| 434.50 | 3.47 | 3.47 |
| 560.62 | 4.52 | 4.52 |
| 532.56 | 4.40 | 4.40 |
| 563.58 | 3.14 | 3.14 |
| 575.63 | 4.65 | 4.65 |
| 513.56 | 3.31 | 3.31 |