Basic Information
ID: ALA4405132
Type: Binding
Description: Inhibition of recombinant human N-terminal GST-tagged HDAC6 (1 to 1125 residues) expressed in baculovirus infected insect cells using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate measured after 1 to 2 hrs by fluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Histone deacetylase 6(ALA1865)
Document: ALA4402587
Inhibition of recombinant human N-terminal GST-tagged HDAC6 (1 to 1125 residues) expressed in baculovirus infected insect cells using fluorogenic peptide p53 residues 379-382 (RHKK(Ac)AMC) as substrate measured after 1 to 2 hrs by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4405132
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 302.37 | 2.58 | 2.58 |
| 348.36 | 2.98 | 2.98 |
| 514.53 | 5.36 | 5.36 |
| 611.61 | 4.86 | 4.86 |
| 575.63 | 4.23 | 4.23 |
| 421.47 | 2.56 | 2.56 |
| 540.63 | 4.11 | 4.11 |
| 562.59 | 3.74 | 3.74 |
| 562.59 | 3.74 | 3.74 |
| 512.57 | 3.83 | 3.83 |
| 586.06 | 4.29 | 4.29 |
| 585.07 | 5.01 | 5.01 |
| 629.60 | 4.94 | 4.94 |
| 575.63 | 3.68 | 3.68 |
| 526.60 | 4.22 | 4.22 |
| 601.67 | 4.80 | 4.80 |
| 575.63 | 4.23 | 4.23 |
| 572.03 | 4.10 | 4.10 |
| 550.62 | 4.36 | 4.36 |
| 562.59 | 3.12 | 3.12 |
| 589.62 | 3.66 | 3.66 |
| 576.62 | 3.51 | 3.51 |
| 571.04 | 4.71 | 4.71 |
| 561.61 | 4.35 | 4.35 |
| 590.60 | 2.43 | 2.43 |
| 515.62 | 4.24 | 4.24 |
| 561.61 | 3.84 | 3.84 |
| 434.50 | 3.47 | 3.47 |
| 541.62 | 3.59 | 3.59 |
| 541.62 | 3.38 | 3.38 |
| 560.62 | 4.52 | 4.52 |
| 532.56 | 4.40 | 4.40 |
| 420.48 | 3.08 | 3.08 |
| 561.61 | 3.92 | 3.92 |
| 563.58 | 3.14 | 3.14 |
| 564.57 | 1.91 | 1.91 |
| 575.63 | 4.65 | 4.65 |
| 513.56 | 3.31 | 3.31 |