Basic Information
ID: ALA4405140
Type: Binding
Description: Inhibition of human PI3Kgamma assessed as reduction in PIP3 product complex formation by measuring displacement of biotin-labelled PIP3 from complex using PIP2 as substrate measured after 30 mins in presence of ATP by HTRF assay
Format: BAO_0000357
Organism: Homo sapiens
Target: PI3-kinase p110-gamma subunit(ALA3267)
Document: ALA4402587
Inhibition of human PI3Kgamma assessed as reduction in PIP3 product complex formation by measuring displacement of biotin-labelled PIP3 from complex using PIP2 as substrate measured after 30 mins in presence of ATP by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4405140
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 302.37 | 2.58 | 2.58 |
| 348.36 | 2.98 | 2.98 |
| 514.53 | 5.36 | 5.36 |
| 611.61 | 4.86 | 4.86 |
| 540.63 | 4.11 | 4.11 |
| 562.59 | 3.74 | 3.74 |
| 562.59 | 3.74 | 3.74 |
| 575.63 | 4.69 | 4.69 |
| 575.63 | 3.68 | 3.68 |
| 526.60 | 4.22 | 4.22 |
| 575.63 | 4.23 | 4.23 |
| 562.59 | 3.12 | 3.12 |
| 589.62 | 3.66 | 3.66 |
| 576.62 | 3.51 | 3.51 |
| 561.61 | 4.35 | 4.35 |
| 590.60 | 2.43 | 2.43 |
| 515.62 | 4.24 | 4.24 |
| 561.61 | 3.84 | 3.84 |
| 541.62 | 3.59 | 3.59 |
| 541.62 | 3.38 | 3.38 |
| 560.62 | 4.52 | 4.52 |
| 532.56 | 4.40 | 4.40 |
| 561.61 | 3.92 | 3.92 |
| 563.58 | 3.14 | 3.14 |
| 564.57 | 1.91 | 1.91 |
| 575.63 | 4.65 | 4.65 |