Basic Information
ID: ALA4405150
Type: Binding
Description: Inhibition of recombinant C-terminal His-fusion tagged and N-terminal Streptavidin2-tagged human HDAC8 (1 to 377 residues) expressed in insect cells at 10 uM using fluorogenic peptide p53 residues 379-382 (RHK(Ac)K(Ac)AMC) as substrate measured after 1 to 2 hrs by fluorescence assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: Histone deacetylase 8(ALA3192)
Document: ALA4402587
Inhibition of recombinant C-terminal His-fusion tagged and N-terminal Streptavidin2-tagged human HDAC8 (1 to 377 residues) expressed in insect cells at 10 uM using fluorogenic peptide p53 residues 379-382 (RHK(Ac)K(Ac)AMC) as substrate measured after 1 to 2 hrs by fluorescence assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4405150
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 302.37 | 2.58 | 2.58 |
| 348.36 | 2.98 | 2.98 |
| 568.62 | 3.80 | 3.80 |
| 562.59 | 3.74 | 3.74 |
| 589.64 | 5.01 | 5.01 |
| 582.65 | 3.48 | 3.48 |
| 551.57 | 3.94 | 3.94 |
| 546.59 | 4.33 | 4.33 |
| 532.56 | 4.40 | 4.40 |
| 575.63 | 4.02 | 4.02 |