Basic Information
ID: ALA4405667
Type: ADME
Description: Inhibition of human liver microsome CYP3A4 using midazolam as substrate incubated for 5 to 20 mins by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4405667
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 434.44 | 4.22 | 4.22 |
| 461.32 | 4.91 | 4.91 |
| 467.88 | 3.42 | 3.42 |
| 467.88 | 3.42 | 3.42 |
| 450.89 | 4.73 | 4.73 |
| 450.44 | 3.51 | 3.51 |
| 477.32 | 4.20 | 4.20 |
| 477.32 | 4.20 | 4.20 |
| 475.34 | 5.10 | 5.10 |
| 417.44 | 3.48 | 3.48 |